รายละเอียดการประชุมวิชาการ

ชื่องานวิจัย ( Article Name )

Cosmetic nanoemulsion containing antioxidant honeysuckle essential oil formulated by ultrasonic emulsification

บทคัดย่อ ( Abstract )

The nanoemulsion containing antioxidant honeysuckle essential oil has been developed by ultrasonic emulsification. Lonicera japonica essential oil was extracted using a supercritical carbon dioxide process in ethanol, yielding 3.25 % w/w. The chemical constituents of the extract were analyzed using GC-MS, and 25 compounds were identified. In the total phenolic content (TPC) and total flavonoid content (TFC) analyses, gallic acid and quercetin were utilized as standards, respectively. The results showed TPC of 53.17 ± 0.17 mg GAE/ g and TFC of 104.37 ± 0.27 mg QE/ g. The antioxidant activity determined by the DPPH assay was expressed in the IC50 value of 20.835 ± 0.51 μg/mL. The facial treatment nanoemulsion containing the extracted essential oil, tween 80 and deionized (DI) water was further formulated by ultrasonic emulsification. The effects of ultrasonic time, surfactant concentration and the mixing ratios of oil and surfactant have been investigated. The suitable formulation of nanoemulsion was 12% v/v surfactant concentration and 1:2 mixing ratio of oil and surfactant with ultrasonic time of 30 min. The results shows that ultrasonic emulsification can reduced the particle size to 71.1 ± 0.42 nm. The polydispersity index of this formulated nanoemulsion is 0.216 ± 0.01 indicating small size distribution of the particle. The results show the advantage of ultrasonic method in development of nanoemulsion which can be applied in drug and cosmetic production.

เเอกสารบทความวิจัย ( Paper )

คลิกเพื่อดาวโหลด

ผู้เขียน ( Authors )

  • Atittaya Meenongwa
  • Wannisa Keawbankrud

วันที่อัพเดตข้อมูลล่าสุด

2023-05-22 07:54:57